250 research outputs found

    Three-way Imbalanced Learning based on Fuzzy Twin SVM

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    Three-way decision (3WD) is a powerful tool for granular computing to deal with uncertain data, commonly used in information systems, decision-making, and medical care. Three-way decision gets much research in traditional rough set models. However, three-way decision is rarely combined with the currently popular field of machine learning to expand its research. In this paper, three-way decision is connected with SVM, a standard binary classification model in machine learning, for solving imbalanced classification problems that SVM needs to improve. A new three-way fuzzy membership function and a new fuzzy twin support vector machine with three-way membership (TWFTSVM) are proposed. The new three-way fuzzy membership function is defined to increase the certainty of uncertain data in both input space and feature space, which assigns higher fuzzy membership to minority samples compared with majority samples. To evaluate the effectiveness of the proposed model, comparative experiments are designed for forty-seven different datasets with varying imbalance ratios. In addition, datasets with different imbalance ratios are derived from the same dataset to further assess the proposed model's performance. The results show that the proposed model significantly outperforms other traditional SVM-based methods

    Experimental study of the vortex-induced vibration of marine risers under middle flow

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    A considerable number of studies for vortex induced vibration (VIV) under uniform flow have been performed. However, investigation of VIV under middle flow is scarce. An experiment for VIV under middle flow was conducted in a deep-water offshore basin. Various measurements were obtained by the fiber Bragg grating strain sensors placed on the riser, and VIV under the effect of middle flow with was investigated. Results show that the riser vibrates at different order natural frequencies along the water depth in the CF and IL directions appearing as the multi-frequencies under middle flow. The variation vortex shedding frequencies along the riser under middle flow may generate different wake modes and vibration modals as the corresponding vortex shedding frequencies approach the riser natural frequencies. The dominant vibration frequency of the entire riser is consistent, and determined by high order natural frequency and the corresponding closing vortex shedding frequencies under the middle flow. Meanwhile, the vibration modal under middle flow appears multi-modals and other lower modal have effect on riser vibration. The VIV mechanism under middle flow possesses some aspects similar to those of uniform flow and several unique features

    Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery

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    BackgroundMalnutrition is common in patients undergoing surgery for cancers and is a risk factor for postoperative outcomes. Body composition provides information for precise nutrition intervention in perioperative period for improving patients’ postoperative outcomes.ObjectionThe aim was to determine changes in parameters of body composition and nutritional status of cancer patients during perioperative period.MethodsA total of 92 patients diagnosed with cancer were divided into gastrointestinal and non-gastrointestinal cancer group according to different cancer types. The patients body composition assessed by bioelectrical impedance vector analysis (BIVA) on the day before surgery, postoperative day 1 and 1 day before discharge. The changes between two groups were compared and the correlation between body composition and preoperative serum nutritional indexes was analyzed.ResultsThe nutritional status of all patients become worse after surgery, and phase angle (PA) continued to decrease in the perioperative period. Fat-free mass (FFM), fat-free mass index (FFMI), skeletal muscle mass (SMM), extracellular water (ECW), total body water (TBW), hydration, and body cell mass (BCM) rise slightly and then fall in the postoperative period in patients with gastrointestinal cancer, and had a sustained increase in non-gastrointestinal patients, respectively (P<0.05). Postoperative body composition changes in patients with gastrointestinal cancer are related to preoperative albumin, pre-albumin, hemoglobin, and C-reactive protein (P<0.05), whereas postoperative body composition changes in patients with non-gastrointestinal cancer are related to age (P<0.05).ConclusionsSignificant changes in body composition both in patients with gastrointestinal cancer and non-gastrointestinal cancer during perioperative period are observed. Changes in body composition for the cancer patients who undergoing surgery are related to age and preoperative serum nutrition index

    Highly active and stable stepped Cu surface for enhanced electrochemical CO₂ reduction to C₂H₄

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    Electrochemical CO₂ reduction to value-added chemical feedstocks is of considerable interest for renewable energy storage and renewable source generation while mitigating CO₂ emissions from human activity. Copper represents an effective catalyst in reducing CO₂ to hydrocarbons or oxygenates, but it is often plagued by a low product selectivity and limited long-term stability. Here we report that copper nanowires with rich surface steps exhibit a remarkably high Faradaic efficiency for C₂H₄ that can be maintained for over 200 hours. Computational studies reveal that these steps are thermodynamically favoured compared with Cu(100) surface under the operating conditions and the stepped surface favours C₂ products by suppressing the C₁ pathway and hydrogen production

    Highly active and stable stepped Cu surface for enhanced electrochemical CO₂ reduction to C₂H₄

    Get PDF
    Electrochemical CO₂ reduction to value-added chemical feedstocks is of considerable interest for renewable energy storage and renewable source generation while mitigating CO₂ emissions from human activity. Copper represents an effective catalyst in reducing CO₂ to hydrocarbons or oxygenates, but it is often plagued by a low product selectivity and limited long-term stability. Here we report that copper nanowires with rich surface steps exhibit a remarkably high Faradaic efficiency for C₂H₄ that can be maintained for over 200 hours. Computational studies reveal that these steps are thermodynamically favoured compared with Cu(100) surface under the operating conditions and the stepped surface favours C₂ products by suppressing the C₁ pathway and hydrogen production

    Bufei Huoxue Capsule Attenuates PM2.5-Induced Pulmonary Inflammation in Mice

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    Atmospheric fine particulate matter 2.5 (PM 2.5) may carry many toxic substances on its surface and this may pose a public health threat. Epidemiological research indicates that cumulative ambient PM2.5 is correlated to morbidity and mortality due to pulmonary and cardiovascular diseases and cancer. Mitigating the toxic effects of PM2.5 is therefore highly desired. Bufei Huoxue (BFHX) capsules have been used in China to treat pulmonary heart disease (cor pulmonale). Thus, we assessed the effects of BFHX capsules on PM2.5-induced pulmonary inflammation and the underlying mechanisms of action. Using Polysearch and Cytoscape 3.2.1 software, pharmacological targets of BFHX capsules in atmospheric PM2.5-related respiratory disorders were predicted and found to be related to biological pathways of inflammation and immune function. In a mouse model of PM2.5-induced inflammation established with intranasal instillation of PM2.5 suspension, BFHX significantly reduced pathological response and inflammatory mediators including IL-4, IL-6, IL-10, IL-8, TNF-α, and IL-1β. BFHX also reduced keratinocyte growth factor (KGF), secretory immunoglobulin A (sIgA), and collagen fibers deposition in lung and improved lung function. Thus, BFHX reduced pathological responses induced by PM2.5, possibly via regulation of inflammatory mediators in mouse lungs
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